When logging into VanillaSoft for the first time in Chrome you will need to allow an "External Protocol Request". This will allow VanillaSoft to dial the phone number associated with the lead on your screen. Click on the phone icon beside the phone number for this request to appear.
In the notification window that appears you will see a description of what the protocol request is and how your VoIP phone will open if the protocol is allowed to run.
You will need to select the option "Remember my choice for all links of this type" and then select the "Launch Application" button.
Once that is done your VoIP phone will load and the phone number associated with the lead will dial out.